Each of the flavonoids inhibited 3βHSD2 and CYP17A1 noticeably, when the inhibition of downstream enzymes, CYP21A2 and CYP11B1, was both of those substrate and flavonoid specific. The dihydrochalcones inhibited the exercise of CYP21A2, although not that of CYP11B1. Though rutin, orientin and vitexin inhibited deoxycortisol conversion by CYP11B1
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